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Tandem pore domain potassium channel
The two-pore-domain potassium channel (not to be confused with the small family of two-pore channels) a family of 15 members form what is known as "leak channels" which possess Goldman-Hodgkin-Katz (open) rectification. These channels are regulated by several mechanisms including oxygen tension, pH, mechanical stretch, and G-proteins . Their name is derived from the fact that the α subunits consist of four transmembrane segments, each containing two pore loops. As such, they structurally correspond to two inward-rectifier α subunits and thus form dimers in the membrane.
Below is a list of the 15 known two-pore-domain human potassium channels:〔
==See also==
* Ion channel
* Potassium channel
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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